Effects of beta-caryophyllene (BCP) in Parkinson's disease
Author: Lucie Garabasova
Beta-caryophyllene (BCP) is a terpene that may have anti-inflammatory and neuroprotective effects in patients with Parkinson's disease, according to preliminary scientific studies. In this article, you will learn how BCP works, how to use it, and what patients have experienced.
Scientific findings on BCP and Parkinson's disease
In recent years, more and more studies have been published that investigate the effects of BCP in relation to neurodegenerative diseases.
Let's take a look at them:
- Anti-inflammatory effects: BCP acts directly on CB2 receptors in the endocannabinoid system (CBD affects multiple receptors at once, so it does not act directly only on CB2) which are mainly associated with the regulation of the immune response and inflammatory processes. Scientists who published a study in 2016 believe that inflammation in nervous tissue plays a significant role in the progression of Parkinson's disease - therefore BCP may be an interesting candidate for supportive therapy.
- Neuroprotection: An October 2024 study published in the Journal of Neuroinflammation suggests that BCP may protect nerve cells from oxidative stress and slow their damage. This is important because Parkinson's disease is associated with the loss of neurons in an area of the brain called the substantia nigra.
- Support for motor functions: Research published in October 2023 shows that BCP can reduce the motor symptoms of the disease – such as stiffness and slowed movements – thanks to a combination of anti-inflammatory and antioxidant effects.
However, it must be emphasized that BCP is not a cure for Parkinson's disease. However, it can act as a complement to classical treatment and improve the quality of life of patients.
How can BCP be used for Parkinson's?
BCP can be supplemented into the body in several ways – both through dietary supplements and commonly available foods (their combination is ideal, specific dietary supplements naturally contain a higher concentration of BCP):
Recommended dietary supplements from Cannadorra:
- BCP Original drops – an ideal start for therapy.
- BCP Extra drops – a 2x stronger combination (compared to Original).
- BCP Good Sleep – a suitable supplement for people suffering from insomnia.
Natural sources in everyday cooking:
- Black pepper – one of the richest sources of BCP.
- Cloves – used not only as a spice, but also in traditional medicine.
- Oregano and basil – herbs with a significant amount of BCP.
- Rosemary – added to food and drinks and can be another source of terpenes.
->>List of plants with the highest BCP content.
Including these foods and hemp products can provide patients with natural support in their daily lives.
Comparison of BCP with other natural substances used in Parkinson's disease
| Substance | Main effects | Advantages | Disadvantages | |
|---|---|---|---|---|
| BCP (beta-caryophyllene) | Anti-inflammatory, antioxidant, neuroprotective | Acts directly on CB2 receptors, well available in cannabis and common herbs | Large-scale clinical studies in Parkinson's disease are still lacking | |
| Curcumin | Strong antioxidant and anti-inflammatory effects | Can protect neurons and reduce alpha-synuclein deposition | Very low bioavailability (poorly absorbed) | |
| Coenzyme Q10 | Antioxidant, supports mitochondria and energy production | Potentially slows disease progression, well researched | Clinical results ambiguous, effect not always proven) | |
| Resveratrol | Antioxidant, anti-inflammatory, possible neuroprotective effect | Natural polyphenol, available in the diet (grapes, berries) | Not enough clinical data yet, effect mainly in experimental studies |
Real experiences of BCP and Parkinson
Practical experiences often complement scientific knowledge and give it a human dimension.
Pavel – experience with CBD/BCP drops
A real experience was shared by a woman who describes the use of BCP drops Extra by her husband Pavel:
“Pavel takes the drops in the morning and always 20 drops in the evening. He says he feels good, sleeps, walks, talks and thinks without any problems. At first I had the feeling that he had difficulty speaking, but that changed over time. With the drops, I also noticed less hand tremor than before.”
Jaroslav – Parkinson's disease
Ms. Jitka Hasíková described the use of CBD drops (20%) for her husband, Mr. Jaroslav Hasík, who suffers from Parkinson's disease:
"I administered C.B.D. drops (20%) according to your recommendation, but I cannot objectively assess whether my husband has experienced any overall improvement in his health... However, my opinion prevails that after BCP drops, my husband is smarter."
Ms. Hasíková adds that they are considering longer-term use and possible dosage adjustments, because they believe in the possibility of improving the quality of life. Although this is an individual experience, it illustrates well that cannabis products can be beneficial for some patients.
Conclusion
Parkinson's disease is a complex disease for which there is currently no simple cure. Natural substances such as beta-caryophyllene (BCP) offer hope for patients in the form of a supportive effect - mainly due to its anti-inflammatory and neuroprotective properties.
Including BCP in the diet or using cannabis products can be a good addition to conventional treatment and contribute to the overall improvement of mental and physical well-being. The research is promising, although further clinical studies are still needed.
💡 If you want to learn more about BCP, we recommend reading a separate article that discusses this substance in more detail.