+420 735 757 631 | info@cannadorra.com

    En  Cz Hu De Pl It Ru
 
Content

Endocannabinoid system - What is it and how it effects human body?

 Write a comment

Endocannabinoid system - What is it and how it effects human body?

 

The Endocannabinoid System (ECS) is a recently discovered group of endogenous cannabinoid receptors found throughout the body. The endocannabinoid receptors that make up the ECS are located in our Central Nervous System (CNS), Peripheral Nervous System (PNS), and Immune System. Our CNS includes our brain and spinal cord, while the PNS acts as a communication network linking our CNS to the rest of our body.

Our brains contain the heaviest concentration of cannabinoid receptors, but there’s no shortage of them in our organs, tissues, glands, and more. The saturation of ECS receptors throughout our body is part of why CBD has so many uses and is so effective.

Components of the endocannabinoid system

The endocannabinoid system is made up of various components that work together and form a complete and fully functional system, which helps to regulate and control the response of the body, associated with the effects of cannabinoids. These components include:

  • Cannabinoid receptors on the surface of the cell wall
  • Endocannabinoids
  • Enzymes

Functions of the endocannabinoid system

Endocannabinoid system is important for many fundamental functions of the human body, such as appetite, immune function, metabolism, digestion of food, pain, sleep, memory, mood, digestion, response to inflammation, and many others. In addition to regulating these basic bodily functions also has an effect on the physiological response to the disease. A very good example is the treatment of cancer and fights against cancer cells. Tumor cells have much more cannabinoid receptors than healthy cells and tissues of the human body. There are also cases where a higher level of endocannabinoids has been demonstrated in people suffering from arthritis, Parkinson's disease, anxiety, or chronic pain. That is why many scientists and medical researchers believe that the function of the endocannabinoid system lies in homeostasis - regulation of the body system and preservation of the balance of the internal environment in all circumstances. Sick body and his condition is in large part a consequence of the inability of the body to achieve homeostasis. Therefore, the role of the endocannabinoid system and its maintaining of the physical balance for medicine is crucial. Endoсannabinoid system is a real treasure for scientists and medical professionals. Although this is a complex system, it plays an important role in many body processes and it seems to have a promising potential in the targeted treatment of many diseases.

Why can cannabinoids have an effect on the human body?

The main reason why cannabinoids such as THC, cannabinol have psychoactive and / or health effects on the human body is that there are places in our body's system that they can react to.It was discovered that THC has the ability to bind to two receptors in the body and activate them as well as they do natural endocannabinoids, that the body itself produces. However, rather than binding directly to them, operate on the principle of the interference effect of the enzyme FAAH, which is responsible for the decomposition of anandamide. When is the effect of the FAAH suppressed, the process of degradation of anandamide is disturbed and this leads to the accumulation of FAAH in the brain – the effect then lasts longer than usual and it causes a feeling of intoxication and psychoactive state, which the user feels? The action against the enzyme FAAH turned out to be an effective means in the struggle with other mental illnesses. Some of the characteristics of the CBD, which suppress the manifestations of anxiety may be associated with the inhibitory effect on the enzyme FAAH and therefore leads to increased presence of endocannabinoids in the bodily system.

 

Questions and Answers

Läs mer...


Cannabidiol(CBD) - What is it and for which disease can be used?

 Write a comment

Cannabidiol(CBD) - What is it and for which disease can be used?

 

Cannabidiol, or CBD for short, naturally occurs within the tiny hairlike structures known as trichomes that grow on hemp and cannabis. The first cannabinoid molecule to be discovered in 1940, researchers have been studying CBD’s numerous health benefits ever since. CBD has been shown to promote healthy sleep, relieve occasional joint pain, speed athletic recovery, enhance relaxation, improve mood, reduce stress and frustration, alleviate occasional nausea, and support immune system health.

Cannabidiol exists in two states, CBD and CBD-a. Both are being studied to discover their individual effects on the body. CBD-a, which grows directly on hemp and cannabis, shows a great potential for different types of treatment. However, its effects haven’t been researched as extensively as CBD. When CBD-a is heated to 248°F, it loses its acid chain in a process called decarboxylation (also referred to as “activation”) and becomes CBD. All our products go through this process. CBD has been well studied and has a more pronounced effect than CBD-a due to more efficiently binding to the body’s Cannabidiol receptors.

An organic product, CBD is a safer, natural alternative to synthetic options with little to no side effects. In hemp’s multi-thousand-year history, there has never been a recorded fatality. While CBD has been shown to be non-toxic even at extreme doses, you should consult your doctor if you plan on taking more than 300mg in a 24 hour period.

Here are 7 medical use for CBD that you might not have known about:

1. Diabetes

In a study using CBD, the development of diabetes in non-obese diabetic mice was prevented. Although there wasn’t a direct effect of cannabidiol on glucose levels, the treatment prevented the production of IL-12 by splenocytes. Preventing this cytokine is important because it plays a huge role in many autoimmune diseases.

2. Acne

A study published in the Journal of Clinical Investigation and the National Institute of Health discovered that CBD can provide treatment for acne. Researchers used hemp-derived cannabidiol on the human sebaceous glands and came to the conclusion that CBD acts as a highly effective

hemostatic and an anti-inflammatory agent by inhibiting lipid synthesis.

3. Fibromyalgia

Common treatments for fibromyalgia are anti-inflammatory medications, opioid pain medications and corticosteroids. A 2011 study that focused on CBD treatment for fibromyalgia produced very promising results for future uses in treatment. Half of the 56 participants used CBD, while the other half used traditional methods to treat their condition. Those that used cannabis saw a great reduction in their symptoms and pain, while those using traditional methods didn’t see much of an improvement.

4. Schizophrenia

In 2012, a group of German researchers published a study in the journal Translational Psychiatry. The potent antipsychotic Amisulpride and CBD were compared between 42 schizophrenia patients. The two treatments were deemed effective, but the short side-effect profile of CBD 

outshined the pharmaceutical option.

5. Post Traumatic Stress Disorder

CBD is known to produce anti-anxiety and anti-inflammatory effects when ingested by slowing everything down and calming the user. Those with PTSD are often overcome with anxiety and stress, so patients frequently find relief by using cannabidiol. The antipsychotic benefits provide a stable mental environment for those that need it most.

6. Crohn’s Disease

Some scientists say CBD could be an effective treatment for bowel diseases like Crohn’s Disease. THC and CBD interact with the system that controls gut function in the body, something that Crohn’s patients suffer issues with. The component of cannabis’ anti-inflammatory ability brings a lot of relief to those suffering from this condition.

7. Multiple Sclerosis

Scientists at the Cajal Institute used animal models and cell cultures to find that CBD reversed inflammatory responses and served as durable protection from the effects of multiple sclerosis. Mice with 10 days of CBD treatment had superior motor skills and showed progression in their condition. Using this information, researchers concluded that CBD has the potential ability to reduce various aspects of MS.

Questions and Answers

Läs mer...


Cannabinoids - What are they and how is their effect on health?

 Write a comment

Cannabinoids - What are they and how is their effect on health?

 

Cannabinoids are organic molecules naturally produced by hemp and cannabis which activate two of the body’s central nervous system receptors: CB1 and CB2.* CB1 receptors are primarily located in the brain, while CB2 receptors are spread throughout the rest of the body. Because CBD does not activate the brain’s CB1 receptors, it is largely non-psychoactive.

Each of the 100+ known cannabinoids have unique receptor interactions, producing individual results. Research has also shown that cannabinoids’ benefits multiply when used together, producing what is called the “entourage effect.”

The most known cannabinoids

From all the cannabinoids, there are only these two are most known: tetrahydrocannabinol (THC) and cannabidiol (CBD). Even though THC has healing effects, it is psychoactive, at the same time it is psychoactive and higher dosage can cause anxiety and paranoia. CBD is not a psychoactive cannabinoid but it does have calming effects and helps to cure different types of inflammations and neurological illnesses.

The Endocannabinoid system

The Endocannabinoid system exists for about 600 million years and was developed even before the Dinosaur era. Since then it is constantly developing and it is present in all animal species. That is why all living organisms, including humans and animals, are capable of absorbing these cannabinoids, that are found only in hemp plants, thanks to the CB1 receptors which are a part of the brain and neurological system and CB2 receptors which are building blocks of the immunity system.

The Endocannabinoid system has a key influence in supporting several important functions of the body, reproduction, emotions, sleep and food intake.
Cannabinoids work in synergy, meaning altogether, and therefore synthetically produced cannabinoids which are usually on sale in pharmacies are not really efficient. It is necessary to use them in a complex way (hemp seeds, hemp seed oil, CBD extract, etc.) so that their healing effects on our health can be absorbed fully.

How do you prefer to use hemp products? Share your experiences in the comment section below!

Questions and Answers

Läs mer...


Hampaprodukter och lagstiftning

 Alla presenterade Hampaprodukter är 100% lagliga enligt EU-lagstiftningen. De är gjorda av lagliga jordbruksstammar av hampa som innehåller en laglig nivå av THC (mindre än 0,2%). Hampafrön används för produktion av olja, protein och även för direkt konsumtion. Hampaörten används för CBD utvinning, te, och salvor & kosmetika. Alla våra produkter är INTE psykoaktiva. 

Cannadorra.com erbjuder ett komplett sortiment av hampa, CBD produkter & livsmedel. All produktion är ekologisk och inom EU. 

CBD produkter Hempate | Hampaolja | Hampafrön | Hampaprotein | Annan hampa | Hampa kosmetika | Hampasalvor

tea, 

Lågprisprodukter

Top! Sale
Hemp Oil Bio Extra Virgin 500 Ml 200x200

Hampaolja BIO extra virgin 500 ml

Hampfröolja är den bästa källan till Omega 3 och 6 fettsyror. Det är ...

Pris
Pre-discount price13,99 €
Pris 12,99 €
 124.7 kr
Top! Sale
150g (bio) Loupana (600x600) 200x200

Skalade Hampafrön BIO 150g

Hampafrön skrov i BIO kvalitet är den bästa källan till omega-3 och ...

Pris
Pre-discount price4,90 €
Pris 3,50 €
 33.6 kr
Top! Sale
Cbd Hemp Tea 35 G 200x200

CBD Hampate 35 g

Hampknoppar och löv med ett högt innehåll av CBD odlas i Tjeckien, 35g.

Pris
Pre-discount price6,99 €
Pris 6,50 €
 62.4 kr
Sale
Ibisek 200x200

Hampate med hibiskus 50g

En härlig kombination av hampblommor och knoppar med Hibiscusblommor från ...

Pris
Pre-discount price4,99 €
Pris 3,99 €
 38.3 kr
Hemp as Natural Medicine

Hemp has great medicinal and nutritional properties. It can be used against many diseases or just as a prevention and source of vitality & longevity.  

Learn how to use it in your everyday life. Get recipes, articles, news, useful information and studies...

Please let us know your email address.
Neplatný vstup
Hemp as Natural Medicine

Hemp has great medicinal and nutritional properties. It can be used against many diseases or just as a prevention and source of vitality & longevity.  

Learn how to use it in your everyday life. Get recipes, articles, news, useful information and studies...

Please let us know your email address.
Neplatný vstup