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The Endocannabinoid System (ECS) is a recently discovered group of endogenous cannabinoid receptors found throughout the body. The endocannabinoid receptors that make up the ECS are located in our Central Nervous System (CNS), Peripheral Nervous System (PNS), and Immune System. Our CNS includes our brain and spinal cord, while the PNS acts as a communication network linking our CNS to the rest of our body.

Our brains contain the heaviest concentration of cannabinoid receptors, but there’s no shortage of them in our organs, tissues, glands, and more. The saturation of ECS receptors throughout our body is part of why CBD has so many uses and is so effective.

Components of the endocannabinoid system

The endocannabinoid system is made up of various components that work together and form a complete and fully functional system, which helps to regulate and control the response of the body, associated with the effects of cannabinoids. These components include:

  • Cannabinoid receptors on the surface of the cell wall
  • Endocannabinoids
  • Enzymes

Functions of the endocannabinoid system

Endocannabinoid system is important for many fundamental functions of the human body, such as appetite, immune function, metabolism, digestion of food, pain, sleep, memory, mood, digestion, response to inflammation, and many others. In addition to regulating these basic bodily functions also has an effect on the physiological response to the disease. A very good example is the treatment of cancer and fights against cancer cells. Tumor cells have much more cannabinoid receptors than healthy cells and tissues of the human body. There are also cases where a higher level of endocannabinoids has been demonstrated in people suffering from arthritis, Parkinson's disease, anxiety, or chronic pain. That is why many scientists and medical researchers believe that the function of the endocannabinoid system lies in homeostasis - regulation of the body system and preservation of the balance of the internal environment in all circumstances. Sick body and his condition is in large part a consequence of the inability of the body to achieve homeostasis. Therefore, the role of the endocannabinoid system and its maintaining of the physical balance for medicine is crucial. Endoсannabinoid system is a real treasure for scientists and medical professionals. Although this is a complex system, it plays an important role in many body processes and it seems to have a promising potential in the targeted treatment of many diseases.

Why can cannabinoids have an effect on the human body?

The main reason why cannabinoids such as THC, cannabinol have psychoactive and / or health effects on the human body is that there are places in our body's system that they can react to.It was discovered that THC has the ability to bind to two receptors in the body and activate them as well as they do natural endocannabinoids, that the body itself produces. However, rather than binding directly to them, operate on the principle of the interference effect of the enzyme FAAH, which is responsible for the decomposition of anandamide. When is the effect of the FAAH suppressed, the process of degradation of anandamide is disturbed and this leads to the accumulation of FAAH in the brain – the effect then lasts longer than usual and it causes a feeling of intoxication and psychoactive state, which the user feels? The action against the enzyme FAAH turned out to be an effective means in the struggle with other mental illnesses. Some of the characteristics of the CBD, which suppress the manifestations of anxiety may be associated with the inhibitory effect on the enzyme FAAH and therefore leads to increased presence of endocannabinoids in the bodily system.

 

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